N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide Epoxide

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide Epoxide
Details:
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate for the synthesis of more complex pharmaceutical compounds. It is used for the synthesis of potential impurities of Bicalutamide (B382000), an anti-androgen, oral nonsteroidal drug used for prostate cancer.
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Description
Technical Parameters

N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide

CAS No.: 90357-51-0

 

[Synonyms]
n-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl oxirane-2-carboxamide
N-4-CYANO-3-(TRIFLUOROMETHYL)PHENYLMETHACRYLAMIDE EPOXIDE
1,2-EPOXY-2-METHYL-N-[4-CYANO-3-(TRIFLUOROMETHYL)]
1,2-Epoxy-2-methyl-N[4-cyano-3(trifluoromethyl)-phenyl] propanamide (Intermediate for Bicalutamide)
1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYL-2-OXIRANE CARBOXAMIDE
N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-Oxiranecarboxamide
N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyl-oxiranecarboxamine
1,2-Epoxy-2-methyl-N-(4-cyano-3-trifluoromethyl)-phenyl)propaneamide
N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]METHACRYLAMIDE EPOXIDE (INTERMEDIATE OF BICALUTAMIDE)
4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide

Melting Point: 174-175 °C


Product Categories: Chemical intermediate for Bicalutamide; Bicalutamide ; API intermediates
Polar Surface Area: 65.42 Å2
Index of Refraction: 1.526
Molar Refractivity: 58.303 cm3
Molar Volume: 189.965 cm3
Surface Tension: 45.759 dyne/cm
Density of N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide (CAS NO.90357-51-0): 1.422 g/cm3
Flash Point: 217.707 °C
Enthalpy of Vaporization: 69.281 kJ/mol
Boiling Point: 436.366 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C

 

[Uses]
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate for the synthesis of more complex pharmaceutical compounds. It is used for the synthesis of potential impurities of Bicalutamide (B382000), an anti-androgen, oral nonsteroidal drug used for prostate cancer.

 

 

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