Compound Sulfamonomethoxine Sodium Powder

What is Compound Sulfamonomethoxine Sodium Powder?

Sulfonamide antibacterial agent. Sulfamonomethoxine inhibits the synthesis of dihydrofolic acid by competing with dihydrofolate synthase; Trimethoprim inhibits dihydrofolate reductase, preventing the reduction of dihydrofolic acid to tetrahydrofolic acid. The combination of sulfamonomethoxine and trimethoprim produces a synergistic antibacterial effect through dual blockade of folate metabolism. Sulfamonomethoxine is well absorbed after oral administration, achieves high blood concentrations, has a low acetylation rate, and its acetylated metabolites are highly soluble in urine, reducing the risk of crystalluria.

What is the Physicochemical Properties of Compound Sulfamonomethoxine Sodium Powder?

This product is a white or off-white powder.

Uses

What is Compound Sulfamonomethoxine Sodium Powder used for?

Sulfonamide antibacterial agent. Used for infections caused by susceptible bacteria in the respiratory, gastrointestinal, and urinary tracts, as well as for coccidiosis and swine toxoplasmosis.

Dosage

How much Compound Sulfamonomethoxine Sodium Powder should be given to an animal?

Oral administration: Single dose: 200–250mg per kg body weight for livestock. Administer twice daily for 3–5 consecutive days.

Side Effects

What are the potential side effects of Compound Sulfamonomethoxine Sodium Powder in different animal species?

Prolonged or high-dose use may cause renal and neurological damage, reduce weight gain, and potentially lead to sulfonamide toxicity.

What are the common dosage forms of Compound Sulfamonomethoxine Sodium Powder?

Composition: 100g of product contains 10g of Sulfamonomethoxine Sodium and 2g of Trimethoprim.

What are the Precautions of Compound Sulfamonomethoxine Sodium Powder?

(1) Continuous administration should not exceed 1 week.

(2) During long-term use, sodium bicarbonate should be co-administered to alkalinize the urine.

(3) Withdrawal period: 28 days.

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