What is Ivermectin and Albendazole Oxide Powder?
Antiparasitic agent. Ivermectin is highly effective against both internal parasites and external arthropods. Its mechanism of action involves stimulating the release of gamma-aminobutyric acid (GABA) from presynaptic neurons, which opens GABA-gated chloride channels. This increases the permeability of the nerve membrane to chloride ions. The chloride influx causes a slight depolarization of the postsynaptic resting potential, disrupting neuromuscular signal transmission and ultimately leading to paralysis and death of the parasite.
Albendazole oxide is the primary active metabolite of albendazole. It acts by binding to β-tubulin in nematodes, inhibiting its polymerization with α-tubulin to form microtubules, thereby disrupting essential cellular processes in susceptible parasites such as mitosis, protein assembly, and energy metabolism. The combination of ivermectin and albendazole oxide provides broad-spectrum anthelmintic efficacy.
What is the Physicochemical Properties of Ivermectin and Albendazole Oxide Powder?
This product is a white or off-white powder.
Uses
What is Ivermectin and Albendazole Oxide Powder used for?
Antiparasitic agent. Used for the control and elimination of internal and external parasites in sheep.
Dosage
How much Ivermectin and Albendazole Oxide Powder should be given to an animal?
Oral administration: Single dose: 100mg per kg body weight for sheep.
Side Effects
What are the potential side effects of Ivermectin and Albendazole Oxide Powder in different animal species?
This product has potential sensitizing and teratogenic effects.
What are the common dosage forms of Ivermectin and Albendazole Oxide Powder?
Composition: 100g of product contains 0.2g of Ivermectin and 5g of Albendazole Oxide.
What are the Precautions of Ivermectin and Albendazole Oxide Powder?
(1) Contraindicated during the lactation period.
(2) Use with caution during the first 45 days of pregnancy in breeding females.
(3) Withdrawal period for sheep: 35 days.
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