TECHNICAL DATA SHEET: AVILAMYCIN PREMIX
1. Product Identification
Product Name: Avilamycin (Feed Grade)
Chemical Class: Orthosomycin Antibiotic
CAS No: 11051-71-1
Molecular Formula: C61H88Cl2O32
Activity: Produced by the fermentation of Streptomyces viridochromogenes.
2. Physical & Chemical Properties
| Property | Specification |
| Appearance | Light brown to brown granular or powder |
| Odor | Characteristic fermentation odor |
| Concentration | Commonly 10% or 20% (w/w) |
| Loss on Drying | ≤ 8.0% |
| Solubility | Insoluble in water; optimized for uniform feed mixing |
| Thermal Stability | Stable under standard pelleting conditions (up to 90°C) |
3. Mode of Action
Avilamycin acts as a potent inhibitor of bacterial protein synthesis. It binds to the 50S ribosomal subunit, specifically interfering with the attachment of aminoacyl-tRNA. This disruption prevents the formation of essential proteins, resulting in the death of susceptible Gram-positive bacteria.
4. Indications & Benefits
Poultry (Broilers): For the prevention and control of Necrotic Enteritis caused by Clostridium perfringens. Improves weight gain and feed efficiency.
Swine: Reduces the incidence of post-weaning diarrhea and improves growth performance in piglets and growing-finishing pigs.
Microbial Balance: Specifically targets pathogenic flora without significant disruption to beneficial lactic acid bacteria.
5. Recommended Inclusion Rates
Note: Inclusion rates should be calculated based on the concentration of the premix (e.g., 10% activity).
| Target Species | Purpose | Active Ingredient (ppm) | Premix (10%) per Ton of Feed |
| Broiler Chickens | Growth Promotion | 5 – 10 ppm | 50 – 100 g |
| Broiler Chickens | NE Prevention | 10 – 20 ppm | 100 – 200 g |
| Piglets (Weaned) | Growth Promotion | 20 – 40 ppm | 200 – 400 g |
| Fattening Pigs | Growth Promotion | 10 – 20 ppm | 100 – 200 g |
6. Stability & Storage
Stability: Highly stable in mash and pelleted feeds. Potency is maintained for at least 24 months from the date of manufacture when stored correctly.
Storage Conditions: Store in a cool, dry, and well-ventilated area. Keep the packaging tightly sealed and away from direct sunlight or moisture.
7. Safety & Regulatory Compliance
Withdrawal Period: 0 Days (In most jurisdictions).
Compatibility: Safe to use in combination with common ionophore coccidiostats and exogenous enzymes.
Non-Human Use: Not utilized in human medicine, reducing the risk of cross-resistance.
Handling: Use standard protective equipment (dust mask, gloves, and goggles) when handling the concentrated premix to avoid inhalation or skin contact.
Disclaimer: The information provided in this Technical Data Sheet is based on current industry knowledge and is intended for informational purposes only. Local regulations regarding inclusion rates and withdrawal periods must be strictly followed.