Monensin Sodium 40% Premix
CAS NO.: 17090-79-8
Specification: 20%, 40% Premix
Characteristics: Yellow-brown or grayish in powder or granular.
PHARMACOLOGICAL ACTION
Monensin is a polyether antibiotic of the ionophore group. It exerts an anticoccidial action against Eimeria tenella, E. acervulina, E. praecox, E. mitis, E. brunetti, E. maxima, E. necatrix in chickens and chickens reared for laying. It is also applied for the prophylactic control of E. gallopavoris, E. meleagrimitis and E. adenoeides affecting turkeys for fattening (up to 16 weeks of age). Its action is connected with the formation of lipophilic complexes with monovalent ions (sodium and potassium), making the membranes of the coccidial cells permeable to the ions mentioned; hence the active sodium and potassium transport is disturbed. Sodium and chloride are accumulated into the cells of the parasites, drawing water into merozoites and sporozoites, causing their swelling and rupture. An additional influence is the impeded transport of carbohydrate and the active sporozoite glycolysis provoked by monensin. Applied at the recommended dosage levels in fowls, monensin is practically not absorbed by the gastrointestinal tract and is not deposited in muscles and internal organs. Nevertheless, a withdrawal period of 1 day is recommended for slaughter of treated chickens for human consumption. The safety margin of the antibiotic is narrow; therefore it must be applied at the accurate dosage levels.
INDICATIONS
Poultry: Prevention of coccidiosis in chickens for fattening and in chickens reared for laying (up to 16 weeks) caused by Eimeria tenella, Eimeria acervulina, E. praecox, E. mitis, Eimeria brunetti, Eimeria maxima, Eimeria necatrix, and in turkeys for fattening caused by Eimeria gallopavonis, Eimeria meleagrimitis and Eimeria adenoeides.
Pigs: For stimulation of weight gain rate and improvement of feed conversion efficiency in pigs (up to three months of age).
Ruminants: For stimulation of weight gain rate and improvement of feed conversion efficiency in ruminants with developed forestomachs (lambs and weaned lambs). For prevention of ketosis in dairy cows.
CONTRAINDICATIONS
Dangerous for equines. Do not feed to chickens or turkeys producing eggs. This additive contains an ionophore: avoid simultaneous administration with tiamulin and monitor for possible adverse reactions when used concurrently with other medicinal substances.
MODE OF ADMINISTRATION for Monensin Sodium 40% Premix Orally, thoroughly mixed into feed.
In order to reach uniform homogenization with feed, it is recommended to mix the measured quantity of the preparation (calculated on the basis of the prescribed dose) on stages in the following order: up to 10 kg feed; up to 100 kg feed; and up to 1000 kg feed.
TARGET SPECIES of Monensin Sodium 40% Premix
Poultry: Chickens for fattening, chickens reared for laying and turkeys for fattening.
Ruminants: beef cattle, dairy cows and lambs. Pigs.
Withdrawal Period: 5 days for chicken and cattle
Package: 25 kg/bag.
Storage: Store in a cool and dry place, in sealed or closed container.
Expiry: Two years.
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