What is Amoxicillin Soluble Powder?
Pharmacodynamics: Amoxicillin is a β-lactam antibiotic with broad-spectrum antibacterial activity. Its antibacterial spectrum and potency are generally similar to ampicillin. It exhibits slightly weaker activity against most Gram-positive bacteria compared to penicillin and is susceptible to penicillinase, rendering it ineffective against penicillin-resistant Staphylococcus aureus. It demonstrates strong efficacy against Gram-negative bacteria such as Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella, and Pasteurella, though these bacteria may readily develop resistance. It is not effective against Pseudomonas aeruginosa. Due to its superior absorption compared to ampicillin in monogastric animals, resulting in higher blood concentrations, it shows better efficacy in treating systemic infections. It is suitable for systemic infections caused by susceptible bacteria, including respiratory, urinary, skin, and soft tissue infections.
Pharmacokinetics: Amoxicillin is highly stable in gastric acid. When administered orally to monogastric animals, 74%–92% of the dose is absorbed. Gastrointestinal contents may affect the rate but not the extent of absorption, allowing administration via medicated feed. After oral administration of an equivalent dose, serum concentrations of amoxicillin are 1.5–3 times higher than those of ampicillin.
What is the Physicochemical Properties of Amoxicillin Soluble Powder?
This product is a white or off-white powder.
Uses
What is Amoxicillin Soluble Powder used for?
β-lactam antibiotic. Used for the treatment of infections caused by amoxicillin-susceptible Gram-positive and Gram-negative bacteria in chickens.
Dosage
How much Amoxicillin Soluble Powder should be given to an animal?
Oral administration: Single dose: 0.2–0.3g per kg body weight for chickens, twice daily for 5 consecutive days;
For medicated drinking water: 0.6g per liter of water for chickens, for 3–5 consecutive days.
Side Effects
What are the potential side effects of Amoxicillin Soluble Powder in different animal species?
May significantly disrupt the normal gastrointestinal flora.
What are the common dosage forms of Amoxicillin Soluble Powder?
Premix: 10%.
What are the Precautions of Amoxicillin Soluble Powder?
Laying hens producing eggs for human consumption must not be used during the laying period.
Not recommended for infections caused by penicillin-resistant Gram-positive bacteria.
(3) Prepare the solution immediately before use.
(4) Withdrawal period for chickens: 7 days.
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