What is Albendazole and Ivermectin Tablets?
Antiparasitic Agent. Albendazole exhibits broad-spectrum anthelmintic activity and demonstrates strong efficacy against nematodes, cestodes, and trematodes. Its mechanism of action involves binding to β-tubulin in helminths, inhibiting its polymerization with α-tubulin to form microtubules, thereby disrupting cellular processes such as mitosis, protein assembly, and energy metabolism within the parasites.
Ivermectin is highly effective against both internal and external parasites, particularly arthropods and nematodes. It is primarily used to control gastrointestinal nematodes, lungworms, and external parasites in animals such as cattle and sheep. Its anthelmintic action is mediated by stimulating the release of gamma-aminobutyric acid (GABA) from presynaptic neurons, which opens GABA-gated chloride channels. The influx of chloride ions reduces membrane resistance, causing a slight depolarization of the postsynaptic membrane potential and disrupting neuromuscular signal transmission. This leads to paralysis and subsequent death or expulsion of the parasites.
What is the Physicochemical Properties of Albendazole and Ivermectin Tablets?
This product is a white or off-white tablet.
Uses
What is Albendazole and Ivermectin Tablets used for?
Anthelmintic Agent. Used for the expulsion or elimination of internal and external parasites in cattle and sheep, including nematodes, trematodes, cestodes, and mites.
Dosage
How much Albendazole and Ivermectin Tablets should be given to an animal?
Oral administration: Single dose: 0.3 tablets per 10kg body weight for cattle and sheep.
Side Effects
What are the potential side effects of Albendazole and Ivermectin Tablets in different animal species?
No adverse reactions have been observed when used at the recommended dosage and administration.
What are the common dosage forms of Albendazole and Ivermectin Tablets?
0.36g (Albendazole 350mg + Ivermectin 10mg).
What are the Precautions of Albendazole and Ivermectin Tablets?
(1) Contraindicated during the lactation period.
(2) The ivermectin component of this product is highly toxic to fish and shrimp. Do not allow drug residues, packaging materials, or animal excreta to contaminate water sources.
(3) Withdrawal period: Cattle and sheep: 35 days.
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