Founded in 2008, Hangzhou Well Sunshine Biotech Co.,Ltd.(Well Sunshine Industrial Co.,Ltd) is a specialized manufacturer of Veterinary products and Feed additives, with three production bases in Zhejiang, Jiangxi and Hubei separately. Our old factory is situated in North Industrial Park, Yongfeng County, Jiangxi province, with over 68,500sqm of lands. Moreover, we also found new GMP approved factory, and this new factory has been put into function now. Well-known for complete production equipments, advanced production methods and complete inspection facilities, we have the good abilities to develop, design and produce products independently. Under the cooperation of Zhejiang University, we are working hard on the development of latest technologies and custom-made products.
Now, we found sales center and R&D center in the downtown of Hangzhou city. In 2015, Well Sunshine Industrial Co.,Ltd was founded by Hangzhou Well Sunshine Biotech Co.,Ltd., which is specialized in expanding international business and strategic cooperation with suppliers.
Why choose us?
Quality Control
We have professional personnel to monitor the production process, inspect the products and ensure that the final product meets the required quality level standards, guidelines and specifications.
One-stop Solution
We can offer a range of services, from consultation and advice to product design and delivery. It is a convenience for the customers, as they can get all the help they need in one place.
24h Online Service
If you have difficulties when using the product, we will respond to your needs as soon as possible and give you the greatest support.
Global Shipping
Our products support global shipping and the logistics system is complete, so our customers are all over the world.
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![Cysteamine HCL]()
Cysteamine HCLCysteamine Hydrochloride is a new formula feed, It Stable in air and processing, Slow release in the small intestine, Good fluidity, Can enhance immunity, Improve meat quality, Enhance activity ofread more -
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![Histidine]()
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![Phenylalanine]()
PhenylalanineL-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and furtherread more -
![Proline]()
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![Isoleucine]()
IsoleucineL-Isoleucine is one of the essential amino acids that cannot be made by the body and is known for its ability to help endurance and assist in the repair and rebuilding of muscle. This amino acid isread more -
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![Aspartic Acid]()
Aspartic AcidAspartic acid is used as an electrolyte supplement for amino acid infusion, potassium, calcium and other inorganic ion supplements, and fatigue restorer. Aspartate potassium magnesium injection orread more
Amino acids are the major nitrogen-containing compounds of plants and are the building blocks of proteins. There are 20 different amino acids normally incorporated into proteins, although they may be subject to alteration afterward, by enzyme reactions such as phosphorylation, methylation, and acetylation. In addition to those in protein, over 300 additional amino acids have been isolated and characterized from plants. With the arrival of even more sensitive analytical techniques, this number is likely to increase. These amino acids may be present in low concentrations and play a vital part as an intermediate in a biosynthetic pathway, e.g., ornithine, homoserine, or cystathionine. In contrast they may act as a major storage form of nitrogen, e.g., canavanine in the seed of Canavalia ensiformis, or may be formed in high amounts in response to an external stress, e.g., γ-aminobutyrate. It is possible that some of these nonprotein amino acids may serve as insecticidal or fungicidal agents.
Benefits of Amino Acid
When you raise the protein level in farm animal feed, farm animals will eat more food and digest it more efficiently, in turn increasing the amounts of amino acids and nutrients available to the animal. This also improves feed efficiency, so there is less waste.
Appropriate amino acid balances support improved growth rate so that animals will wean and reach mature weight early. Additionally, well-fed calves, piglets and chicks tend to be healthier and larger as adults, producing more and experiencing disease at a lower rate.
The most prominent reason for culling cows is reproduction — if a cow doesn't calve, it doesn't produce milk. Conversely, the higher an animal's production potential, the higher the value of the pregnancy. By increasing the amount and the quality of amino acids in feed, especially methionine and lysine, studies have shown an improvement in pregnancy rates, which not only contribute to herd numbers but also improve milk production, increasing profitability.
Regardless of how much a cow is producing, it costs the same to keep it in the herd due to operating costs, fixed overhead costs, maintenance requirements and dry matter. To make the most of that cow, it is important that she produces enough milk to offset any costs of increasing feed quality. By improving the ratio of amino acids in the diet, you can increase cow's milk production cost-effectively and achieve a positive return on investment.
Higher incidence of disease leads to diminished production and higher maintenance costs, reducing the profitability of your farm. Additionally, a disease can impact the future production potential of a segment of your herd, negatively affecting production in the long-term. By ensuring that your herd's diet is complete with balanced amino acid levels to support the animals’ metabolism and immune response, you can protect the health of your farm animals and minimize costly diseases.
Phenylalanine
Your body turns this amino acid into the neurotransmitters tyrosine, dopamine, epinephrine, and norepinephrine. It plays an integral role in the structure and function of proteins and enzymes and the production of other amino acids.
Valine
This is one of three branched-chain amino acids (BCAAs) on this list. That means it has a chain branching off from one side of its molecular structure. Valine helps stimulate muscle growth and regeneration and is involved in energy production.
Threonine
This is a principal part of structural proteins such as collagen and elastin, which are important components of your skin and connective tissue. It also plays a role in fat metabolism and immune function.
Tryptophan
Often associated with drowsiness, tryptophan is a precursor to serotonin, a neurotransmitter that regulates your appetite, sleep, and mood.
Methionine
This amino acid plays an important role in metabolism and detoxification. It’s also necessary for tissue growth and the absorption of zinc and selenium, minerals that are vital to your health.
Leucine
Like valine, leucine is a BCAA that is critical for protein synthesis and muscle repair. It also helps regulate blood sugar levels, stimulates wound healing, and produces growth hormones.
Isoleucine
The last of the three BCAAs, isoleucine is involved in muscle metabolism and is heavily concentrated in muscle tissue. It’s also important for immune function, hemoglobin production, and energy regulation.
Lysine
Lysine plays major roles in protein synthesis, calcium absorption, and the production of hormones and enzymes. It’s also important for energy production, immune function, and collagen and elastin production.
Histidine
Your body uses this amino acid to produce histamine, a neurotransmitter that is vital to immune response, digestion, sexual function, and sleep-wake cycles. It’s critical for maintaining the myelin sheath, a protective barrier that surrounds your nerve cells.
Application of Amino Acid
Active Pharmaceutical Ingredients (apis)
There are pharmaceutical products that make use of amino acids themselves, and products that are synthesized and manufactured using amino acids as starting materials. Amino Acids are also used in infusion solutions, in addition to tablet and granulated forms, and are an essential part of modern medical treatments.
Medical Foods / Medical Nutrition
Amino Acids are used as a way to provide a concentrated, specific and efficient intake of required nutrient components in medical foods for malnourished patients, elderly people with lower digestive capabilities, as well as in other uses.
Dietary Supplement / Health Foods / Functional Foods & Beverages
Amino Acids are used for compensating amino acid deficiencies, as well as in supplements that make use of the specific function of amino acids. Products are sold in tablet, granular and capsule forms. These products were once mostly used by athletes, but they are now popular among the wider public for everyday workout and health maintenance.
There are also functional food and beverage products that contain amino acids for functions similar to those found in health foods.
Cosmetics
Amino Acids are used in cosmetics for their unique moisturizing effect and pH levels. Amino acid derivatives are also used for their stability and absorbency.
Culture Medium
Recently, pharmaceutical products research and manufacture using cell culture process have become very popular. Amino Acids are essential components of cell culture medium. Amino Acids are considered to be indispensable to cell growth and production of antibodies and proteins.
Problems Caused By Amino Acid Deficiencies in Farm Animals
Changes In Intake
One of the first and most important signs of an amino acid imbalance in the feed of a herd is a reduction in feed intake. Although most animals will initially eat more food to try to compensate for the deficiency, after a few days the animals will decrease their food intake substantially. This decrease in intake occurs because amino acid imbalances in food result in reduced hunger in many species. This can contribute to further nutritional deficiencies and subsequently lead to low performance and health problems.
Low Body Weight
In both young and adult animals, amino acid deficiencies contribute to low body weight and a general reduction in muscle development. For younger animals, this can have long-lasting effects, including a reduced growth rate, a prolonged time to reach maturity and reduced size at maturity. This low body weight cannot be fixed through force-feeding3. Studies have shown that even when animals are forced to eat sufficient calories if the diet is missing amino acids, the animal will still experience morphological problems and will often continue to lose weight.
Reduced Production
In dairy cows, an inadequate supply of amino acids will result in reduced milk production. In poultry, an overall reduction in the size and quantity of eggs produced has been reported. Amino acids are the building blocks of tissues and milk proteins, so that any deficiency will reduce production.
Disease
Amino acids are essential for animal health, contributing to the maintenance of numerous metabolic functions, including maintenance and immune responses. If certain amino acids are missing from an animal's diet, it may experience reduced immune and metabolic responses, leaving its body more vulnerable to diseases, and, in severe cases, mortality.
The industrial application of amino acids for feed has an almost 60-year history (Toride, 2004). First, in the late 1950s and 1960s, methionine (Met), produced by chemical synthesis, began to be used in poultry feed. Production of lysine (Lys) by a fermentation process was started in the 1960s. In the late 1980s, threonine (Thr) and tryptophan (Trp) also produced by the fermentation process were introduced.
With feed formulation becoming increasingly advanced, further amino acids such as valine (Val), isoleucine (Ile), leucine (Leu), arginine (Arg), histidine (His) and cystine (Cys) are considered to be used in feed. Besides the introduction of new free amino acids in feed for monogastric animals (poultry and swine), the introduction of amino acids in feed for ruminants (in particular dairy cows) takes place.
How Amino Acid Works
Adding amino acids to feed reduces feed costs, improves feed efficiency, and enhances animal growth. Lysine, Methionine, Threonine, Tryptophan and Valine are commonly used in feeds, since these essential amino acids tend to be deficient in natural feedstuffs.
Effect of Amino Acid Feed on Livestock
Livestock are generally mammals, such as pigs, and the amount of weight gain and daily deposited protein increases as the level of lysine in the feed increases. It does not decrease until the maximum need is met; and the amount of feed and carcass fat per kilogram of weight gain decreases with increasing lysine levels.
For cattle, methionine and lysine are limiting amino acids for milk protein synthesis. Increasing the amount of amino acids that reach the small intestine of the cow, especially essential amino acids, increases the amount of milk protein.
In addition, supplementation with methionine and cystine increases wool break strength, elongation and length. Supplying a sufficient amount of amino acids, especially sulfur-containing amino acids, increases the density and diameter of the rabbit hair.
How to Choose Amino Acid Correctly
Estimate The Amino Acid Content In Raw Materials
Amino acids are naturally present in raw materials in variable quantities and qualities. For an optimal nutritional strategy, it is therefore important to quantify the content of essential amino acids in feedstuffs.
Formulate Feeds On Digestible Amino Acid Values
The digestible content of each amino acid in an animal feed is a predictive criteria for performance. Since the usual criterion for crude protein is only the nitrogen quantity multiplied by the coefficient 6.25, it is not a good indicator for risk management.
Use Amino Acids Effectively, Balance Is Essential
Good amino acid nutrition occurs by taking into account the dietary intakes in essential amino acids. The latter can vary according to the species as well as the animal’s physiological stage.
Identify Limiting Amino Acids In Order To Optimize Performance
If one of the essential amino acids is not provided in an optimal quantity, it then becomes the limiting factor in the feed formula. Identifying the most limiting amino acid in a feed is equivalent to detecting the progress targets in feed and animal performance. Any incremental change in the limiting amino acid nutritional level will make it possible to obtain better performances. Moreover, by choosing an adequate amino acid level, one limits the risks of deficiency linked with the variability in feed manufacturing and the variability of feedstuffs used in the formula. The limiting amino acid depends on the animal’s needs and the type of raw materials used. Defining the limiting amino acid is therefore contextual and must be studied on a case-by-case basis.
Understand How To Evaluate Responses To Amino Acids
At the R&D level, evaluating the response to an amino acid requires respecting certain model protocols in order to avoid too much variability in the results, which would then be difficult to transpose into practice. Since intakes in amino acids are studied in relation to Lysine, it is important that in the dose response experiments the first limiting factor is the studied amino acid followed by Lysine. If this is respected, this method makes it possible to estimate the response to an amino acid and find the balance point between an amino acid and the referent one (Lysine).
Minimize Formulation Risks
The results from our amino acid nutritional research make it possible to establish rules regarding responses and standards. However, this is not enough to establish the correct levels that must be used in feed formulas. Indeed, it is important to integrate farming contexts (raw materials, performance and economics) as well as clearly identifying the objective to which one must respond.
Choose The Optimal Level Of Lysine
Lysine is the first limiting amino acid in pigs and the second in poultry. The direct correlation between the intake of Lysine and muscle mass turns it into a crucial element in amino acid nutrition. Since other amino acids are expressed as a ratio of Lysine, it is essential to choose the Lysine level that best corresponds to the need of the animal without being limiting. Consequently, the growing use of feed-use amino acids (L-Lys, L-Thr, L-Trp, L-Val, etc.) makes it possible to get as close as possible to animals’ needs without increasing the levels of dietary proteins.
Take Into Account The Functional Roles Of Amino Acids
Although standardized through the concept of the ideal protein, requirements in amino acids also depend on their functional roles and the desired objectives. It is then necessary to study the interactions between all of the amino acids and their functional roles.
Use Amino Acids To Improve The Sustainability Of Livestock Industries
Using amino acids makes it possible to correctly respond to animals’ needs while reducing the levels of dietary proteins. The benefits go beyond animal performance and are essential in terms of sustainable development.
Predict Performance Through The Net Energy System
A nutritional imbalance between energy and amino acids intakes can have numerous consequences on the animal and its environment: increase in the animals’ fat ratio or nitrogen excretion accompanied with economic losses and negative environmental impacts.
FAQ
As one of the leading amino acid manufacturers and suppliers, we warmly welcome you to wholesale custom made amino acid from our factory. All products are with high quality and competitive price.
L Tryptophan, L Valine