What is Oxfendazole Tablets?
This product contains oxfendazole, which is the sulfoxide metabolite of fenbendazole formed in vivo. Its mechanism of action involves binding to tubulin in nematodes to exert anthelmintic effects. Its antiparasitic spectrum is not as broad as that of albendazole, but its potency is slightly stronger.
Unlike most other benzimidazole drugs, oxfendazole is relatively well absorbed from the gastrointestinal tract. The elimination half-lives in sheep and goats are 7.5 hours and 5.25 hours, respectively. After absorption, oxfendazole is metabolized to fenbendazole sulfone, which still retains anthelmintic activity.
What is the Physicochemical Properties of Oxfendazole Tablets?
This product is a white or off-white tablet.
Uses
What is Oxfendazole Tablets used for?
Anthelmintic agent. Primarily used for the expulsion of nematodes and cestodes.
Dosage
How much Oxfendazole Tablets should be given to an animal?
Oral administration: Single dose: 1 tablet per 10kg body weight for horses; 0.5 tablets for cattle; 0.5–0.75 tablets for sheep; 0.4 tablets for pigs; 1 tablet for dogs.
Side Effects
What are the potential side effects of Oxfendazole Tablets in different animal species?
(1) High doses in dogs may cause anorexia.
(2) May cause aplastic anemia in dogs.
(3) Has teratogenic effects.
What are the common dosage forms of Oxfendazole Tablets?
0.1g.
What are the Precautions of Oxfendazole Tablets?
(1) Not for use in cattle or sheep producing milk for human consumption during the lactation period.
(2) Contraindicated in horses intended for human consumption.
(3) A single dose is generally ineffective in dogs; must be administered for 3 consecutive days.
(4) Withdrawal period: Cattle, sheep, and pigs: 7 days.
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