What is Prednisone Acetate Tablets?
This product itself is pharmacologically inactive and requires conversion to prednisolone in vivo to exert its effects. It exhibits anti-inflammatory, anti-allergic, antitoxin, and anti-shock properties. Its anti-inflammatory and gluconeogenic activities are 4 times more potent than those of hydrocortisone, while its water/sodium retention and potassium excretion effects are weaker than those of hydrocortisone. Due to its strong anti-inflammatory and anti-allergic actions with fewer side effects, it is widely used in clinical practice. It promotes the conversion of proteins to glucose, reduces glucose utilization by tissues, and increases blood glucose and liver glycogen levels, potentially leading to glucosuria.
What is the Physicochemical Properties of Prednisone Acetate Tablets?
This product is a white tablet.
Uses
What is Prednisone Acetate Tablets used for?
Glucocorticoid agent. It exerts anti-inflammatory, anti-allergic, and glucose metabolism-modulating effects. Used for inflammatory and allergic diseases, as well as bovine ketosis and ovine pregnancy toxemia.
Dosage
How much Prednisone Acetate Tablets should be given to an animal?
Oral administration: Single dose: 20–60 tablets for horses and cattle; 2–4 tablets for sheep and pigs; 0.1–0.4 tablets per kg body weight for dogs and cats.
Side Effects
What are the potential side effects of Prednisone Acetate Tablets in different animal species?
(1) Exhibits significant water and sodium retention as well as potassium excretion effects.
(2) Has potent immunosuppressive effects.
(3) High-dose use in late pregnancy may induce abortion.
(4) Long-term or high-dose administration may predispose to adrenal cortical insufficiency.
What are the common dosage forms of Prednisone Acetate Tablets?
5mg.
What are the Precautions of Prednisone Acetate Tablets?
(1) Contraindicated in pregnant animals during early and late gestation.
(2) Contraindicated in animals with osteoporosis and during vaccination periods.
(3) Contraindicated in animals with severe hepatic dysfunction, or during fracture treatment and wound healing periods.
(4) For acute bacterial infections, it should be used in combination with antibacterial agents.
(5) Abrupt discontinuation after long-term therapy is not recommended; dosage should be gradually reduced until cessation.
(6) Withdrawal period: Cattle, sheep, and pigs: 0 days.
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